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PROJECTS

EucoHIV is an independent self-constituted study group aiming at increasing scientific knowledge on HIV coreceptor usage and its clinical significance, including an appropriate use of coreceptor antagonists.


EucoHIV has been funded by an unrestricted educational grant by ViiV Healthcare in 2011.


EuResist Network coordinates and financially administrates the project and  collects the data required for EucoHIV into a database developed as an extension of the EuResist Integrated Database (EIDB).

The PhyloGeoTool realised by the REGA group on the Euresist Integrated DB is available online.

It allows you to phylogeographycally explore the EIDB and to place on its phylogenetic tree your aminoacid sequence.

PUBLICATIONS

Clinical use, efficacy, and durability of maraviroc for antiretroviral therapy in routine care: A European survey

De Luca A, Pezzotti P, Boucher C, Döring M, Incardona F, Kaiser R, Lengauer T, Pfeifer N, Schülter E, Vandamme AM, Zazzi M, Geretti AM; EucoHIV Study Group.

PLoS One. 2019 Nov 21;14(11):e0225381. doi: 10.1371/journal.pone.0225381. PMID: 31751385; PMCID: PMC6874206.

Efficacy and durability of maraviroc (MVC) in antiretroviral treatment (ART) regimens across Europe

 Andrea De Luca, Patrizio Pezzotti, Charles Boucher, Matthias Döring, Francesca Incardona, Rolf Kaiser, Thomas Lengauer, Nico Pfeifer, Eugen Schuelter, Anne-Mieke Vandamme, Maurizio Zazzi and Anna Maria Geretti for the EucoHIV study group

EACS 2017

PhyloGeoTool: interactively exploring large phylogenies in an epidemiological context.

Pieter Libin, Ewout Vanden Eynden, Francesca Incardona, Ann Nowé, Antonia Bezenchek, EucoHIV study group, Anders Sönnerborg, Anne-Mieke Vandamme, Kristof Theys and Guy Baele.

Accepted in Bioinformatics 2017

Maraviroc Use and Outcomes Across Europe - the European Coreceptor (EUCO) HIV Cohort Study

A.M. Geretti, M. Doring, E. Schülter, C. Boucher, F. Incardona, R. Kaiser, T. Lengauer, N. Pfeifer, A.M. Vandamme, M. Zazzi, EUCO-HIV Study Group

EACS 2015

EucoHIV WorkPackages

Work Package 1

Project Coordination

 

Francesca Incardona

EuResist Network

Work Package 2

Database running and maintenance

Eugen Schulter

University of Cologne - Germany

 

Tamar Lavee

IBM Haifa - Israel

Work Package 3

Data collection 

Anna Maria Geretti

University of Liverpool

United Kingdom

Work Package 4

Geno2pheno algorithm

Thomas Lengauer

Nico Pfeifer

Alexander Thielen

Max Planck Institute

for Informatics - Germany

 

Rolf Kaiser

University of Cologne - Germany

Work Package 5

Quality assurance for

gp120 sequencing

Rolf Kaiser

University of Cologne - Germany

Work Package 6

Research proposals

Maurizio Zazzi

University of Siena - Italy

Work Package 7

Training and Dissemination

Charles Boucher

Annemarie Wensing

Antoinet van Kessel

European Society for translational Antiviral Research 

Work Package 8

Phylogenetic tools

Anne-Mieke Vandamme

Pieter Libin

Philippe Lemey

University of Leuven - Belgium

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